·From: NYC & Northern NJ. Take Interstate 80 west to Route 33 South to Route 22 West, to Route 512/Center Street exit. Turn right onto Route 512. At the first traffic light turn right onto Gateway Drive, the Best Western Lehigh Valley Hotel & Conference Center is on the left. ·From: Philadelphia. Take Interstate 476 North to Exit 56 (Lehigh Valley Exit). Follow Route 22 East for nine miles to Route 512/Center Street Exit. Turn right, travel north on Route 512, go to second traffic light and turn right onto Gateway Drive, the Best Western Lehigh Valley Hotel & Conference Center is on the left. ·From: NYC & Central NJ. Take Interstate 95 South to Interstate 78 West. (Continue into Pennsylvania) to Route 33 North. Take Route 33 North to Route 22 West. Proceed west on Route 22 for nine miles to Route 512/Center Street Exit. Turn right, travel north on Route 512, go to second traffic light and turn right onto Gateway Drive, the Best Western Lehigh Valley Hotel & Conference Center is on the left. ·From: Harrisburg Area. Take Interstate 81 North to Interstate78 East to Route 22 East. Follow Route 22 East for twelve miles to Route 512/Center Street Exit. Turn right, travel north on Route 512, go to second traffic light and turn right onto Gateway Drive, the Best Western Lehigh Valley Hotel & Conference Center is on the left.