·From: Miami on I-95 North. Take Exit 273. Take US1 West to State Route 100 West in Bunnell for 30 miles. The Best Western Inn of Palatka is on the left. ·From: Ocala on I-75 North. Take Exit 350. Take State Route 200 to State Route 40. Turn left onto State Route 315 to Orange Springs. Take 310 to Highway 19 and turn left onto State Route 100. Turn right and head 4 miles to the Best Western Inn of Palatka. ·From: Jacksonville on I-95. Going South take Exit 311 onto State Route 207. Head west to US 17 and turn right. The Best Western Inn of Palatka is approximately 1 mile. ·From: Lake City on I-75 South. Take Exit 82. Take Highway 90 to 100 East and drive approximately 70 miles. In Palatka, cross the St. Johns River Memorial Bridge and the Best Western Inn of Palatka is on the right.